The specimen is a cornea from a 67 year old Caucasian female from San Diego with history of chronic corneal ulcer (x 6 months) and status post Lasik surgery a few months before. Cultures and smears were all negative. The patient was treated with antibiotics and anti-amebic drugs empirically for 3-6 months. Initially there was clinical suspicion for amebic keratitis despite the negative corneal smear examination.

An Unusual Lesion of the Cornea

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What is your diagnosis?