This is a lung mass taken from an 80 year old female. The lung mass was initially noted on chest x-ray. Subsequent CT exam demonstrated two lesions, one in the right upper lobe (2.0 cm) and one in the right lower lobe (1.0 cm). CT-guided fine needle aspiration was performed on the upper lobe lesion with a diagnosis of malignant cells, non-oat cell. The patient was taken to surgery and had a right lower lobe lobectomy.

Lung Masses

Image 1-Larger lung lesion in the right upper lobe.


Image 2-Higher magnification of the larger lung lesion.


Image 3-Higher magnification of the larger lung lesion.


Image 4-Higher power magnification of same lesion.

Image 5-Larger lung lesion stained with antibodies to pan-cytokeratin.

Image 6-Larger lung lesion stained with chromagranin A.


Image 7-Smaller lung lesion in the right lower lobe.


Image 8-Smaller lung lesion, higher magnification.

Image 9-Smaller lung lesion stained with antibodies to pan-cytokeratin.

Image 10-Smaller lung lesion stained with antibodies to chromogranin A.

What is your diagnosis?