Got Path? Pathology Inc. Consensus Conference 07.12.2006

General Surgical Pathology Case Studies

Figure 1 Figure 2 Figure 3 Figure 4	Pathology Inc. Consensus Conference July 19th, 2006
	Fascinoma #1 Dr. Mary Beth Shwayder presented a beautiful example of an invasive micropapillary carcinoma of the breast (Figures 1-4). It is important to separate this histopathologic subtype from conventional infiltrating ductal subtypes because of the potentially aggressive behavior these tumors exhibit (see reference below Pettinato etal). Intraepithelial Lymphocytosis in Architecturally Preserved Proximal Small Intestinal Mucosa: An Increasing Diagnostic Problem With a Wide Differential Diagnosis Dr. Shitabata reviewed the diagnostic criteria presented in this recent article. Although increased intraepithelial lymphocytosis has been recognized as an early diagnostic aid for the diagnosis of celiac sprue, there are several other important disease states that have been associated with this finding, in the setting of architecturally preserved small intestinal mucosa. The Power Point presentation is available for review with any web-based browser. Journal Articles Reviewed Invasive micropapillary carcinoma of the breast: clinicopathologic study of 62 cases of a poorly recognized variant with highly aggressive behavior. Am J Clin Pathol, 2004 Jun;121(6):857-66 Pettinato G, Manivel CJ, Panico L, Sparano L, Petrella G. Intraepithelial Lymphocytosis in Architecturally Preserved Proximal Small Intestinal Mucosa: An Increasing Diagnostic Problem With a Wide Differential Diagnosis. *Archives of Pathology and Laboratory Medicine:* Vol. 130, No. 7, pp. 1020–1025. Ian Brown, MBBS, FRCPA; Mari Mino-Kenudson, MD; Vikram Deshpande, MD; Gregory Y. Lauwers, MD

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First Posted July 19, 2006

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